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本文对48例干眼病患者的红细胞免疫和T淋巴细胞免疫功能进行了测定和对比研究。红细胞C3b受体花环率均值为6.98±3.12%,红细胞免疫复合物花环率均值为8.12±3.53%,对照组分别为12.80±5.35%和5.20±1.15%,二项均有显著性差异(P≤0.01)。T细胞亚群均值为:CD358.12±4.76%,CD438.92±3.92%,CD837.58±5.61%,CD4/CD8=1.03±0.69,对照组分别为67.98±5.80%,45.42±5.24%,29.24±3.02%,1.55±1.73,各项均有显著性差异(P≤0.01)。结果表明,干眼病患者的红细胞免疫功能和T淋巴细胞亚群均异常,且两者呈一致性关系,机体免疫调节机制紊乱。
In this paper, 48 cases of dry eye patients with erythrocyte and T lymphocyte immune function were measured and compared. The average rate of rosette C3b receptor rosette was 6.98 ± 3.12%, the average value of rosette immune complex rosette was 8.12 ± 3.53%, and the control group was 12.80 ± 5.35% and 5.20 respectively ± 1.15%, two significant differences (P≤0.01). The average of T lymphocyte subsets were: CD358.12 ± 4.76%, CD438.92 ± 3.92%, CD837.58 ± 5.61%, CD4 / CD8 = 1.03 ± 0.69, the control group were 67.98 ± 5.80%, 45.42 ± 5.24%, 29.24 ± 3.02% and 1.55 ± 1.73, all of which had significant difference (P≤0.01). The results showed that the patients with dry eye had abnormal erythrocytic immune function and T lymphocyte subsets, both of which were in a consistent relationship and the mechanism of immune regulation was disordered.