最近,Spiliotis及Bercu等报告一组生长发育迟缓儿童,其血浆GH水平极低,但胰岛素等激发试验反应正常。作者称此状态为GH神经分泌性功能紊乱(GH neurosecretory dysfunction,GHND)。诊断GHND常需静脉插管作24小时血浆GH定量分析,取血量大,操作繁复,患儿很难接受。本文采用高敏单克隆酶免疫法(EIA)测定 Recently, Spiliotis and Bercu et al reported a group of children with growth retardation who had very low plasma GH levels but insulin and other provocation tests that responded normally. The authors call this state GH neurosecretory dysfunction (GHND). Diagnosis of GHND often need intravenous catheter for 24-hour plasma GH quantitative analysis of blood volume, complicated operation, the child is difficult to accept. In this paper, high sensitivity monoclonal enzyme immunoassay (EIA) determination