胰岛是一个内分泌细胞团,作为一个整体对各种生理因素发生反应。近来发现胰岛中邻近细胞间的复杂排列,而提出以下可能:即细胞与细胞间的联系有助于协调各种激素的分泌量。作者根据解剖学所见,提出将胰岛按功能分成两个亚单位。一个是周边的不同细胞单位,由A、B及D细胞组成,D细胞分泌生长激素释放抑制素(Somatostotin),能抑制邻近的A细胞分泌胰高血糖素及B细胞分泌胰岛素;二是位于胰岛中心的同种细胞单位,大部分由B细胞组成。大鼠、中国田鼠及小鼠的分泌高血糖素的A细胞位于胰岛的最周边部位;D细胞形成稀疏层,紧密接触外面的A细胞层;D细胞层之内的中心块,主要是由B The islet is an endocrine cell mass that, as a whole, reacts to various physiological factors. Recent discovery of the intricate arrangement of adjacent cells in the islets suggests the possibility that the cell-cell association helps to coordinate the secretion of various hormones. According to anatomical findings, the authors propose that islets be divided into two subunits by function. One is the surrounding different cells, composed of A, B and D cells, D cells secrete somatostatin (Somatostotin), can inhibit the secretion of glucagon adjacent B cells and B cells secrete insulin; the second is located in the islet Center of the same kind of cells, most of the B cells. Rat, Chinese voles and mice glucagon A cells located in the most peripheral part of the islets; D cells form a sparse layer, close contact with the outer A cell layer; D cell layer within the central block, mainly by the B