患者女性,38岁。因口服氯氮平及硝基安定各100片约10小时于1992年2月10日入院。既往有精神分裂症病史1年,长期服硝基安定及氯氮平,每晚各1片能入眠。2月9日晚10点常规口服氯氮平及硝基安定不能入眠。后自服氯氮平及硝基安定各100片约20分钟后入眠。8小时后其家属发现病人口吐白沫,不省人事,大小便失禁,急送我院,门诊诊为重度安眠药中毒,给予清水洗胃,静滴美解眠,速尿及输液等治疗。查体:体温36.5℃,脉率126/min,呼吸30/min,血 Patient female, 38 years old. Due to oral clozapine and nitrazepam each 100 about 10 hours on February 10, 1992 admission. Past history of schizophrenia 1 year, long-term service nitrozepam and clozapine, each one night can sleep. At 10 o’clock on February 9 routine oral clozapine and nitrazepam can not sleep. After taking clozapine and nitrazepam each 100 about 20 minutes after sleep. 8 hours later, his family members found that the patient vomited at the mouth, unconsciousness, incontinence, urgently sent to our hospital, outpatient clinics as severe sleeping pills poisoning, give clear water gastric lavage, intravenous hypnosis, furosemide and infusion therapy. Physical examination: body temperature 36.5 ℃, pulse rate 126 / min, breathing 30 / min, blood