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目的：提高对肝内小占位性病变诊断的敏感性和特异性。方法：采用CDFI初筛，结合DSA、DTLPCT等项特殊检查，对肝癌病危人群、干部体检和普通B超所发现各种良恶性肝内≤3cm小结节进行联合检测，发现48例SHCC，并与50例肝硬化结节、炎性肉芽肿或腺瘤样增生等良性病变进行对照。结果：CDFI可见两组血流信号、多项血流参数等均有显著差异。DSA检查，80％SHCC可见特征性肿瘤血管和肿瘤染色。LPCT反DTLPCT对SHCC检测率高达94．7％，直径最小仅2～3mm。DTLPCT除可见癌灶内碘油进一步聚集增浓外，其周边及子灶部分显示更为完整。并提出SHCC大体可分成包膜完拉和不完整两种类型，其临床表现、Child分级、生物学行为和预后等均有很大差异。结论：上述多种方法联合检测，可起到互补和提高早期诊断水平的作用。
Objective: To improve the sensitivity and specificity of diagnosis of small occupying lesions in the liver. METHODS: Using CDFI primary screening, combined with DSA, DTLPCT and other special examinations, a total of ≤3cm nodules were detected in different groups of benign and malignant hepatocellular carcinomas in the HCC population, cadre physical examination, and general B-ultrasound, and 48 cases of SHCC were found. It was compared with 50 benign nodules, inflammatory granuloma or adenomatous hyperplasia. Results: There were significant differences in blood flow signals and multiple blood flow parameters between the two groups. DSA examination showed that 80% of SHCC had characteristic tumor vascular and tumor staining. LPCT anti-DTLPCT detection rate of 94.7% for SHCC, the smallest diameter of only 2 ~ 3mm. In DTLPCT, in addition to the further accumulation and thickening of lipiodol in the visible lesions, the periphery and the subfoci part of the lesion showed more completeness. It is proposed that the SHCC can be roughly divided into two types: complete and incomplete capsules. The clinical manifestations, Child classification, biological behavior and prognosis are all very different. Conclusion: The combination of multiple methods mentioned above can play a complementary role in improving early diagnosis.