论文部分内容阅读
目的 :研究翼状胬肉的发生与角膜缘干细胞缺乏的相关性。方法 :通过对 5 4例翼状胬肉手术病例切除的标本进行病理检查 ,在镜下观察翼状胬肉颈部组织的上皮细胞和正常角膜缘结膜上皮细胞以及干细胞的移行变化。结果 :翼状胬肉头颈部表面上皮细胞层数减少 ,形态扁平 ,部分萎缩 ;翼状胬肉颈部与正常角膜缘球结膜的交界处上皮细胞排列层数逐渐移行减少 ,基底膜破坏 ,细胞排列不规则 ,缺乏基底的柱状细胞 (角膜缘基底部柱状细胞包含角膜缘干细胞与短暂扩充细胞 )。结论 :角膜缘干细胞的缺乏和破坏可能是翼状胬肉发生的重要因素之一。
Objective: To study the correlation between the occurrence of pterygium and the lack of limbal stem cells. Methods: Fifty-four cases of pterygium surgery were examined by pathology. The epithelial cells and normal limbal conjunctival epithelial cells and stem cell migration were observed under the microscope. Results: The number of epithelial cells on the surface of the head and neck of the pterygium decreased, and the morphology was flat and partially atrophied. The number of epithelial cells in the junction of the pterygium neck and normal conjunctiva decreased gradually, the basement membrane was destroyed, Irregular, lacking basal columnar cells (limbal basement basal cells including limbal stem cells and transient expansion of cells). Conclusion: Lack of limbal stem cells and destruction may be one of the important factors in the occurrence of pterygium.