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目的分析2016年镇江市疑似预防接种异常反应(AEFI)的发生特征,评价监测系统运行情况、提高免疫规划(NIP)疫苗的安全性和预防接种服务质量。方法通过国家AEFI监测系统收集2016年镇江市报告的个案数据,采用描述方法对相关指标进行流行病学分析。结果镇江市共报告AEFI个案2 150例,总报告发生率为304.81/10万剂。反应分类以一般反应最为多见,2 060例,占95.81%;异常反应88例,占4.09%;偶合症2例,占0.10%;涉及疫苗23种,其中报告个案最多的无细胞百白破疫苗,929例,占43.21%;AEFI报告数男、女性别比为1.18∶1,≤1岁占81.40%,7月报告发生数最多;反应时间集中在接种后0~3 d内,占96.84%;临床诊断以发热/红肿/硬结反应病例最多,有2 060例,占95.81%。结论镇江市AEFI监测系统运行正常,预防接种服务质量良好,目前使用的NIP疫苗安全性良好。
Objective To analyze the characteristics of suspected AEFI in Zhenjiang City in 2016, evaluate the operation of monitoring system, improve the safety of immunization program (NIP) vaccine and prevent vaccination service. Methods The national AEFI monitoring system was used to collect the reported case data of Zhenjiang City in 2016, and the descriptive method was used to carry out epidemiological analysis of related indicators. Results A total of 2150 AEFI cases were reported in Zhenjiang City. The total reported incidence was 304.81 / 10 million doses. The most common reaction classification was 2 060 cases, accounting for 95.81%; 88 cases were abnormal reaction, accounting for 4.09%; 2 cases were coupled disease, accounting for 0.10%; 23 cases were involved in vaccine, Vaccine, 929 cases, accounting for 43.21%; AEFI reported a number of male and female ratio of 1.18:1, ≤1 years accounted for 81.40%, the largest number reported in July; reaction time concentrated within 0-3 days after inoculation, accounting for 96.84 %; Clinical diagnosis of fever / redness / induration reaction cases, there are 2 060 cases, accounting for 95.81%. Conclusion The AEFI monitoring system in Zhenjiang City is in normal operation and the vaccination service is of good quality. The NIP vaccine currently used is safe.