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早在25年前,人们发现溶酶体阳离子蛋白(LCP)是中性白细胞(NL)的重要杀菌物质之一,甚至浓度很低时,对各种革兰氏阳性和阴性菌、念珠菌等都有强大的杀菌力,而且不产生抗药性。LCP 的杀菌作用是由于破坏细菌大分子合成、离子输送和氧的利用所致.作者检查75例(年龄20～60岁)呼吸病患者,其中急性局灶性肺炎10例,大叶性肺炎15例,单纯性(卡他性)慢性支气管炎(慢支)18例,化脓性慢支12例,阻塞性慢支20例。对照组为14例健康人。用细胞化学染色法检查 NL 的 LCP 含
Twenty-five years ago, LCP was found to be one of the key bactericidal substances of neutrophils (NL), even against very low concentrations of various Gram-positive and -negative bacteria, Candida, etc. Have a strong bactericidal power, but does not produce resistance. The bactericidal effect of LCP is due to the destruction of bacterial macromolecular synthesis, ion transport and oxygen utilization caused by the authors examined 75 cases (aged 20 to 60 years) respiratory patients, including 10 cases of acute focal pneumonia, lobar pneumonia 15 Cases, simple (catarrhal) chronic bronchitis (chronic bronchitis) in 18 cases, purulent chronic bronchitis in 12 cases, obstructive chronic bronchitis in 20 cases. The control group was 14 healthy people. Cytochemical staining was used to examine the LCP content of NL