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本文报告8例恶性网状细胞增生病,均经尸检病理证实。在诊断上,经多年临床实践,认为异常网状细胞及/或多核巨型网状细胞,对恶网病有比较特异性的诊断价值。异常网状细胞与吞噬性网状细胞同时发现,则对诊断有更大价值。并提出与反应性网状细胞增多症的鉴别,供临床诊断上的参考。在病理上,认为增生异常网状细胞所在部位及病变程度,依次为脾、淋巴腺、肝、骨髓、肺及肾等,尤以脾和淋巴腺改变突出,受侵犯器官分布不一致,且同一病例不同部位病变不一,还有不同程度吞噬现象。淋巴腺、脾的正常组织结构普遍破坏、消失。此外,简单介绍了关于组织化学检查对本病诊断意义的研究。
This article reports 8 cases of malignant reticular cell hyperplasia, confirmed by autopsy. In the diagnosis, after many years of clinical practice, that abnormal reticular cells and / or multi-core giant reticular cells, have a more specific diagnostic value of the disease. Abnormal reticulocytes and phagocytic reticulocytes found simultaneously, then the diagnosis of greater value. And proposed and reactive reticulocytosis identification for clinical diagnosis on the reference. Pathologically, it is considered that the site of abnormal reticular cells and the degree of lesion are spleen, lymph, liver, bone marrow, lung and kidney, especially the spleen and lymph gland. The organs affected by the invasion are inconsistent and the same case Different parts of the disease vary, there are different degrees of phagocytosis. Lymph gland, spleen normal tissue structure generally destroyed, disappeared. In addition, a brief introduction on the significance of histochemical examination on the diagnosis of the disease.