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目的了解本院输血不良反应情况,掌握妇产科患者输血不良反应的特征,从而降低输血不良反应率。方法回顾性统计和分析本院2011-2015年用血人次和输血不良反应情况。结果 2011-2015年共计发生输血不良反应51人次,其中异体输血47人次(3.25%),自体输血4人次(0.56%),总输血不良反应率为2.36%;非溶血性发热反应26人次(50.99%),过敏反应21人次(41.18%)。悬浮红细胞引起不良反应数最多(58.82%),其次为新鲜冰冻血浆(19.61%);机采血小板引起的不良反应率最高(8.70%),自体血液最低(0.56%)。悬浮红细胞引起的不良反应以非溶血性发热反应为主(占80.00%),新鲜冰冻血浆、冷沉淀和机采血小板均只引起过敏反应。异体输血中,产科输血不良反应率为3.04%,妇科为5.44%。总输血中,产科输血不良反应率为2.22%,过敏占多数;妇科为2.74%,以非溶血性发热反应为主。输血量≥1 600 m L输血不良反应率5.21%,以过敏反应为主;输血量<1 600 m L发生输血不良反应率1.92%,非溶血性发热反应为主。结论 2011-2015年本院妇产科患者输血不良反应率高于全国平均。产科和大量输血患者输血不良反应以过敏反应为主,妇科患者以非溶血性发热反应为主,自体输血不良反应率最低。在临床工作中要预防和减少输血不良反应的发生,根据不同的科别和出血量估计及输血种类进行针对性预防。
Objective To understand the adverse reactions of blood transfusion in our hospital and to master the characteristics of transfusion adverse reactions in obstetrics and gynecology patients so as to reduce the adverse reaction rate of transfusion. Methods Retrospective statistics and analysis of our hospital from 2011 to 2015 blood transfusion and adverse reactions. Results A total of 51 adverse transfusions were observed in 2011-2015, of which 47 were allogeneic (3.25%), 4 (0.56%) were transfusions, and 2.36% were noninvasive. The number of non-hemolytic reactions was 26 (50.99 %), 21 allergic reactions (41.18%). The number of adverse reactions caused by suspended erythrocytes was the highest (58.82%), followed by fresh frozen plasma (19.61%), the highest rate of adverse reactions (8.70%) caused by organism platelets and the lowest (0.56%) with autologous blood. Adverse reactions caused by suspended erythrocytes were dominated by non-hemolytic fever (80.00%). Fresh frozen plasma, cryoprecipitate and organic platelets only caused anaphylactic reaction. In allogeneic blood transfusions, the adverse reaction rate of obstetric transfusion was 3.04% and that of gynecology was 5.44%. In total blood transfusions, the rate of adverse reactions in obstetric transfusion was 2.22% and the majority was allergy; the gynecology was 2.74%. The non-hemolytic fever was the main reaction. Blood transfusion ≥1 600 m L transfusion adverse reaction rate of 5.21%, mainly allergic reactions; transfusion less than 1 600 m L transfusion adverse reactions rate of 1.92%, non-hemolytic fever-based response. Conclusion The rate of adverse reactions of blood transfusion in obstetrics and gynecology patients in our hospital from 2011 to 2015 is higher than the national average. Adverse reactions in patients with obstructive and transfusion-based blood transfusion were mainly anaphylactic reactions. Non-hemolytic fever was the main cause of gynecological patients, with the lowest rate of ADRs. In clinical work to prevent and reduce the incidence of adverse reactions of blood transfusion, according to different subjects and the amount of bleeding and blood transfusion type targeted prevention.