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通过观察三组不同疾病的老年患者外周血白细胞介素Ⅱ（ＩＬ－２）和自然杀伤（ＮＫ）细胞活性的相互关系，并与健康老人作对比，提示，ＩＬ－２及ＮＫ细胞活性在健康老人组最高，糖尿病组次之，慢阻肺组明显减低（Ｐ＜０．０５），消化道肿瘤组最低（Ｐ＜０．０１）；ＩＬ－２对健康老人及各组老年患者ＮＫ细胞活性均有明显促进作用；ＩＬ－２及ＮＫ细胞活性在各老年组均呈直线正相关，且相关系数有显著意义。结论：老年病人（消化系统肿瘤，慢阻肺、糖尿病）细胞活性低于健康老年人，通过增加内源或外源的ＩＬ－２均能提高机体免疫应答能力，从而减少感染及肿瘤的发生率，达到延缓生命的作用。
By observing the relationship between interleukin-2 (IL-2) and natural killer (NK) cell activity in peripheral blood of three elderly patients with different diseases and comparing with healthy elderly, it is suggested that the activity of IL-2 and NK cells in healthy elderly (P <0.05), and the lowest in gastrointestinal tumor group (P <0.01). The activity of NK cell in healthy elderly and elderly patients in each group was significantly lower than that in the control group IL-2 and NK cell activity in all elderly groups showed a linear positive correlation, and the correlation coefficient was significant. CONCLUSION: The cell activity of elderly patients (digestive system tumors, COPD, diabetes) is lower than that of healthy elderly people, and can increase the body’s immune response ability by increasing endogenous or exogenous IL-2, thus reducing the incidence of infection and tumor , To delay the role of life.