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患者女,60岁,躯干、四肢皮肤干燥、脱屑伴瘙痒1年余,加重1月。近5月出现咳嗽、咳痰,加重伴胸闷、憋气一周。皮肤组织病理:表皮内水肿,棘层肥厚,皮突延长,真皮血管周围见大量嗜酸性粒细胞。胸部CT:肺恶性肿瘤。胸部肿物病理示:低分化腺癌,局灶伴鳞癌分化。诊断:嗜酸细胞增多性皮炎;肺癌。
Female patient, 60 years old, trunk, limbs, dry skin, scaling and itching more than 1 year, increased in January. Nearly 5 months cough, sputum, increased with chest tightness, suffocation for a week. Skin histopathology: intraepidermal edema, acanthosis, lenticel lengthening, see a large number of eosinophils around the dermal vessels. Chest CT: Lung cancer. Chest mass pathology: poorly differentiated adenocarcinoma, focal with squamous cell carcinoma differentiation. Diagnosis: eosinophilic dermatitis; lung cancer.