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感染性角膜炎仍是世界性的常见致盲眼病,中国作为发展中国家,特别是在许多农村地区,感染性角膜病的发病率仍较高。近年随着广谱抗生素和糖皮质激素在临床的广泛应用,导致角膜感染性病原体谱以及对各种药物的敏感性与以往相比有显著变迁,同时随着基础研究和药物学的进展,许多新观点和新药物引入临床。在加强和规范我国感染性角膜病的诊治方面应注意:加强流行病学研究和回顾性研究;重视病原体实验室诊断;规范使用眼用抗生素;注意药物的角结膜毒性。
Infectious keratitis is still a common worldwide cause of blindness. As a developing country in China, especially in many rural areas, the incidence of infectious keratopathy is still high. In recent years, with the widespread use of broad-spectrum antibiotics and glucocorticoids in clinical practice, the spectrum of corneal infectious pathogens and the sensitivity to various drugs have changed significantly compared with the past. With the progress of basic research and pharmacology, many New ideas and new drugs introduced into the clinic. In strengthening and regulating the diagnosis and treatment of infectious corneal disease in our country should pay attention to: to strengthen epidemiological studies and retrospective studies; emphasis on laboratory diagnosis of pathogens; regulate the use of ophthalmic antibiotics; pay attention to the drug’s keratoconjunctival toxicity.