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发明摘要本发明涉及到新型多组分晶体的制备及其应用,用于通过同时作用于由肌肉紧张或关节变性病造成的疼痛以及由发炎过程所造成的疼痛,来治疗疼痛病况,特别是不明原因的疼痛。所述新型多组分晶体含有[2-氨基-6-(4-氟-苯甲基氨基)-吡啶-3-基]氨基甲酸乙酯(氟吡汀)和2-[2-[(2,6-二氯苯基)-氨基]-苯基]醋酸(双氯芬酸)作为唯一的活性成分组合,并可以通过以1.0:0.9-1.0:1.1的摩尔比将所述两种组分溶于惰性有机溶剂中,并随后对所述复合化合物进行结晶而制得。
Summary of the Invention The present invention relates to the preparation of novel multicomponent crystals and their use for the treatment of pain conditions, in particular unknown, by acting simultaneously on the pain caused by muscle tone or joint degenerative disease and the pain caused by the inflammatory process Cause of pain. The novel multicomponent crystal contains ethyl [2- amino-6- (4-fluoro-benzylamino) -pyridin-3- yl] carbamate (flupirtine) and 2- [2 - [ , 6-dichlorophenyl) -amino] -phenyl] acetic acid (diclofenac) as the sole active ingredient combination and can be prepared by dissolving the two components in an inert ratio of 1.0: 0.9 to 1.0: 1.1 in molar ratio In an organic solvent, and then crystallizing the composite compound.