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在1994年生产中，有7批精白类纯度低于法规规定的1500Lf／mg．PN的水平。将这些低纯度的精白类再精制是十分必要的。精制白喉类毒素再精制的方法有：pope的硫酸铵分段法，肖锡岭等的中空维超滤法，以及阚毓筠等的SephadexG200分离法等。由于第3法操作复杂，收率较低，且不适用
In 1994 production, there are 7 batchs of purity less than 1500Lf / mg regulated by the law. PN level. It is very necessary to re-refine these low-purity whiteners. Purified diphtheria toxoid re-refining methods are: pope ammonium sulfate fractionation, Xiao Xiling and other hollow-dimensional ultrafiltration, and Kan Yukun and other SephadexG200 separation and so on. Due to the complex operation of the third method, the yield is low and does not apply