论文部分内容阅读
目的 调查儿童肺炎支原体(MP)感染的临床特点。方法 对2001 年1 月1 日至2003 年12月31日,在本院住院的689例MP感染患儿的发病、临床表现、经过及预后等方面进行回顾性分析。结果 (1)2001~2003年,每年住院的患病率依次为3.0%,6.45%及13.67%,MP肺炎占住院肺炎患儿的比例依次为6.9%、13.3%及37.2%。男女之比为1.89∶1,其中57.3%为3岁以下患儿。(2)首发症状:以咳嗽多见(占48.%),其他依次为发热(38 6%)、皮疹(5.7%)、哮喘(3 3%)、鼻塞(1 2%)、关节痛(0.9%)、抽搐(0.9%)及肉眼血尿、腹泻、心律失常、胸闷(各0.3%)。(3)主要诊断:表现为肺炎80.83%,其中有肺外表现者30.16%;支气管炎及哮喘各4 06%,上呼吸道感染2.61%,过敏性紫癜2.32%,血小板减少性紫癜及心肌炎各1.74%,传染性单核细胞增多症1.45%,川崎病1.31%,脑炎1.16%,肾炎0.87%。(4)X线改变:支气管肺炎28 9%,局灶片状均一实变影20.9%,弥漫性间质改变16.1%,支气管周围炎9.3%,肺门周围模糊影9.1%,仅为肺纹理增粗4.1%,肺部无改变11 6%。(5)实验室检查:ALT升高35.1%,血细胞学检查有30%单核细胞升高。(6)治疗及预后:2~12周不等的大环内酯类抗生素治疗,治愈率达95 4%,1 例死亡。结论 (1)2001~2003年MP感染住院患病率逐年升高。男性及3 岁以下患儿为主。(2)MP感?
Objective To investigate the clinical features of Mycoplasma pneumoniae (MP) infection in children. Methods A retrospective analysis was made on the incidence, clinical manifestation, course and prognosis of 689 children with MP infection hospitalized in our hospital from January 1, 2001 to December 31, 2003. Results (1) From 2001 to 2003, the prevalences of hospitalizations were 3.0%, 6.45% and 13.67%, respectively. The proportion of MP pneumonia in hospitalized children with pneumonia was 6.9%, 13.3% and 37.2% respectively. The ratio of men to women was 1.89: 1, of which 57.3% were children under 3 years of age. (2) The first symptom was cough (48.%), followed by fever (38.6%), rash (5.7%), asthma (33%), stuffy nose (12%), joint pain 0.9%), convulsions (0.9%) and gross hematuria, diarrhea, arrhythmia, chest tightness (0.3% each). (3) The main diagnosis: the performance of pneumonia 80.83%, of which 30.16% were extrapulmonary manifestations; bronchitis and asthma 466%, upper respiratory tract infection 2.61%, 2.32% of anaphylactoid purpura, thrombocytopenic purpura and myocarditis 1.74 %, Infectious leukocytosis 1.45%, Kawasaki disease 1.31%, encephalitis 1.16%, nephritis 0.87%. (4) X-ray changes: 28 9% of bronchial pneumonia, 20.9% of uniformed focal laminar consolidation, 16.1% of diffuse interstitial changes, 9.3% of bronchial inflammation, and 9.1% of blurring around hilar, Thicker 4.1%, no change in lung 11 6%. (5) laboratory tests: ALT increased 35.1%, hemocytosis 30% mononuclear cells increased. (6) treatment and prognosis: macrolide antibiotics ranging from 2 to 12 weeks, the cure rate was 95 4%, 1 patient died. Conclusions (1) The prevalence of hospitalization for MP infection increased year by year from 2001 to 2003. Men and children under 3 years of age. (2) MP sense?