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目的探讨急性心肌梗死患者不同空腹血糖水平与预后的关系,其中预后情况包括住院治疗期间和出院后1年内的严重心律失常、心力衰竭、心源性休克和猝死的发生率。方法将某院2009.01.01～2010.10.01入院急性心肌梗死患者960例(否认既往糖尿病史),并依据入院时空腹血糖值(FBG)情况分组。规定FBG≤5.6mmol/L为A组;5.6mmol/L﹤FBG≤7.8mmol/L为B组;7.8mmol/L﹤FBG≤11.1mmol/L为C组;FBG﹥11.1mmol/L为D组。所有病例均随访1年以上,分别统计其发病入院系统治疗期间和病情控制后出院1年内严重心律失常、心力衰竭、心源性休克和猝死等主要心血管事件(MACE)的发生率,并对其进行统计学分析,探讨急性心肌梗死患者不同血糖水平与预后的关系。结果系统治疗期间和病情控制后出院1年内各组的主要MACE事件发生率随空腹血糖水平升高而提高。结论空腹血糖水平越高,系统治疗期间和病情控制后出院1年内严重心律失常、心力衰竭、心源性休克和猝死等主要MACE事件发生率越大,提示预后越差。
Objective To investigate the relationship between different fasting blood glucose levels and prognosis in patients with acute myocardial infarction. The prognosis includes the incidence of severe arrhythmia, heart failure, cardiogenic shock and sudden death during hospitalization and within 1 year after discharge. Methods A total of 960 hospitalized patients with acute myocardial infarction from 2009.01.01 to 2010.10.01 were enrolled in this study. The history of previous diabetes was denied. The patients were divided into group according to fasting blood glucose (FBG) at admission. The FBG≤5.6mmol / L is the group A; 5.6mmol / L 11.1mmol / L is the D group . All patients were followed up for more than 1 year, and the incidences of major cardiovascular events (MACE) such as severe arrhythmia, heart failure, cardiogenic shock and sudden death within 1 year after their admission and hospitalization were monitored and their condition were controlled respectively. The statistical analysis to explore the relationship between different blood glucose levels and prognosis in patients with acute myocardial infarction. Results The incidence of major MACE events in each group increased with fasting blood glucose level within 1 year after system treatment and after disease control. Conclusions The higher the fasting blood glucose level, the greater the incidence of major MACE events such as heart failure, cardiogenic shock and sudden death within 1 year after discharge from the system during treatment and after disease control, suggesting that the prognosis is worse.