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目的探究全凭静脉麻醉与静吸复合麻醉对胃肠肿瘤患者术后认知功能的影响。方法选择2015年11月—2017年1月本院收治的胃肠肿瘤切除手术患者80例作为研究对象,随机分为对照组和观察组各40例。对照组患者给予静吸复合麻醉,观察组予以全凭静脉麻醉,比较两组患者手术前后认知功能及拔管时间、呼吸恢复时间、苏醒时间。计量资料采用t检验,P<0.05为差异有统计学意义。结果对照组患者拔管时间、呼吸恢复时间及苏醒时间分别为(21.26±5.67)、(15.64±3.67)、(32.12±10.31)min,观察组分别为(17.64±4.61)、(13.26±3.14)、(18.89±8.64)min,两组相比差异均有统计学意义(均P<0.05)。手术结束后1 h,对照组患者注意力、定向力、语言能力及行为能力评分分别为(4.97±0.98)、(4.47±0.32)、(4.61±0.13)、(4.53±0.46)分,均低于观察组的(5.94±0.78)、(5.46±0.67)、(5.34±0.63)、(5.23±0.32)分,差异均有统计学意义(均P<0.05)。结论全凭静脉麻醉可有效改善胃肠肿瘤患者术后认知功能障碍,缩短其术后拔管时间、呼吸恢复时间及苏醒时间,提高患者生活质量,值得临床推广与应用。
Objective To investigate the effects of total intravenous anesthesia and static inhalation anesthesia on postoperative cognitive function in patients with gastrointestinal tumors. Methods Eighty patients with gastrointestinal tumor resected in our hospital from November 2015 to January 2017 were randomly divided into control group and observation group of 40 cases. Patients in the control group were given intravenous anesthesia combined with intravenous anesthesia in the observation group. The cognitive function, extubation time, respiratory recovery time and recovery time were compared between the two groups before and after operation. Measurement data using t test, P <0.05 for the difference was statistically significant. Results The extubation time, respiration recovery time and recovery time in the control group were (21.26 ± 5.67), (15.64 ± 3.67) and (32.12 ± 10.31) min, respectively, and those in the observation group were (17.64 ± 4.61) and (13.26 ± 3.14) , (18.89 ± 8.64) min respectively, there was significant difference between the two groups (all P <0.05). At 1 h after surgery, the scores of attention, orientation, verbal ability and behavioral competence of the control group were (4.97 ± 0.98), (4.47 ± 0.32), (4.61 ± 0.13) and (4.53 ± 0.46) points, respectively, (5.94 ± 0.78), (5.46 ± 0.67), (5.34 ± 0.63) and (5.23 ± 0.32) points in the observation group, the differences were statistically significant (all P <0.05). Conclusion Intravenous anesthesia can effectively improve postoperative cognitive dysfunction, shorten the postoperative extubation time, respiratory recovery time and recovery time, and improve the quality of life of patients with gastrointestinal cancer, deserving clinical application and promotion.