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目的观察2型中老年糖尿病患者合并抑郁症的临床干预意义。方法回顾我院2008年3月至2010年9月期间诊治的中老年糖尿病患者中合并抑郁症患者33例,随机分成两组,干预组20例,治疗糖尿病同时给予抗抑郁治疗,对照组13例,只进行常规糖尿病治疗。观察患者干预前后综合临床治疗效果(住院日、出院时血糖)、长期(3个月和6个月)生活质量改善(抑郁评分)、血糖的控制(HbA1c)及胰岛素用量的变化。结果与对照组相比,抗抑郁干预组住院日缩短(P<0.05)、干预后生活质量明显改善(P<0.01)、血糖控制更好(P<0.01)、胰岛素用量减少(P<0.05),具有统计学意义。结论中老年2型糖尿病抑郁症发病率高,给予抗抑郁干预临床效果明显。
Objective To observe the clinical intervention significance of type 2 diabetes mellitus patients with depression. Methods A retrospective study from March 2008 to September 2010 in our hospital diagnosis and treatment of middle-aged and elderly diabetic patients with depression in 33 cases, were randomly divided into two groups, the intervention group of 20 patients with diabetes mellitus while giving antidepressant treatment, the control group of 13 patients , Only conventional diabetes treatment. The clinical effects (hospital stay, blood glucose at discharge), quality of life improvement (depression score), blood glucose control (HbA1c) and insulin dosage in long term (3 months and 6 months) were observed before and after treatment. Results Compared with the control group, the length of stay in the anti-depression intervention group was shorter (P <0.05), the quality of life improved significantly after intervention (P <0.01), the blood glucose control was better (P <0.01) ,has statistical significane. Conclusion The incidence of depression in middle-aged and elderly patients with type 2 diabetes is high, and the clinical effect of anti-depression intervention is obvious.