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目的探讨CAG方案治疗老年初治急性髓性细胞白血病的临床疗效。方法选取我院收治的48例行CAG方案治疗的老年初治急性髓性细胞白血病(AML)患者,并对其临床资料进行回顾性分析。结果本组48例患者中26例患者完全缓解,13例患者部分缓解,其治疗总有效率为81.25%;骨髓抑制为化疗后主要不良反应,且患者均未发生明显肝肾功能损害。结论给予老年初治急性髓性细胞白血病患者CAG方案治疗可取得良好的治疗效果,且毒副作用小,临床效果显著,值得推广和应用。
Objective To investigate the clinical efficacy of CAG regimen in the treatment of newly diagnosed acute myeloid leukemia in the elderly. Methods Forty-eight patients with acute myeloid leukemia (AML) admitted to our hospital undergoing CAG regimen were selected and their clinical data were retrospectively analyzed. Results In the 48 patients, 26 patients were completely relieved and 13 patients were partially relieved. The total effective rate was 81.25%. The bone marrow suppression was the main adverse reaction after chemotherapy, and no significant liver and kidney dysfunction occurred in all patients. Conclusion The treatment of acute myeloid leukemia in elderly patients with acute myeloid leukemia can achieve a good therapeutic effect, with small toxic and side effects, significant clinical effect, and worthy of promotion and application.