【摘 要】
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Dear Editor,rnAerobic exercise is well known to improve cognitive functions including hippocampus-dependent spatial mem-ory[1]and object recognition[2].Regarding the molecular mechanisms,the indispensable role of brain-derived neu-rotrophic factor (BDNF)
【机 构】
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Department of Rehabilitation,The Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou
论文部分内容阅读
Dear Editor,rnAerobic exercise is well known to improve cognitive functions including hippocampus-dependent spatial mem-ory[1]and object recognition[2].Regarding the molecular mechanisms,the indispensable role of brain-derived neu-rotrophic factor (BDNF) in governing exercise-induced neural plasticity has been demonstrated for the improve-ment of learning and memory[3].Our recent study further demonstrated the activation of mechanistic target ofrapamycin pathways downstream of BDNF to drive synaptic protein synthesis upon persistent exercise [4],but leaving the effect of exercise on the post-translational modification of proteins largely unknown.
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