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本文报告５０例子宫内膜腺癌ＤＮＡ含量，并选１１例非癌病变为对照。所有病例存档蜡块标本，重新作５μｍ切片，Ｆｅｕｌｇｅｎ反应染色，以医用细胞图像处理系统，作细胞ＤＮＡ分析。结果：子宫内膜癌２Ｃ（２１．８６％），３～４Ｃ（４１．７７％），５Ｃ（１３．７５％），＞５Ｃ（２２．６０％）；增生期宫内膜依ＤＮＡ含量顺序为２４．１３％、６１．３６％、１１．０３％、３．４６％；囊性宫内膜增殖为２７％、６０．３７％、７．９６％、４．６２％；宫内膜增生过长为２６．９５％、６５．５％、６．６％、０．９％，其ＤＮＡ含量在５Ｃ以上宫内膜癌为３６．６％，增生期宫内膜、囊性宫内膜增殖和宫内膜增生过长，依次含量分别为１４．４９％、１２．５８％和７．５％；子宫内膜癌组织学仅见Ⅲ级，未出现Ⅳ级，ＤＮＡ含量＞５Ｃ，Ⅰ级占２７．６６％，Ⅱ级占２９．３４％，Ⅲ级含量剧增达６２．２４％。说明非整倍体机率随病分级的增加而增加，并认为在临床上作细胞ＤＮＡ测定，有助于客观判断分析肿瘤生物学特性。
This article reports 50 cases of endometrial adenocarcinoma DNA content, and eleven cases of non-cancerous lesions as a control. All cases were preserved wax specimens, re-made 5μm sections, Feulgen reaction staining, medical cell image processing system for DNA analysis. Results: The endometrial carcinoma of the endometrium in the proliferative phase was found to have a higher level of DNA (21.86%), 3 ~ 4C (41.77%), 5C (13.75%) and> 5C Which was 24.13%, 61.36%, 11.03% and 3.46% respectively. The cystic endometrial hyperplasia was 27%, 60.37%, 7.96% and 4.62% Too long for 26.95%, 65.5%, 6.6%, 0.9%, the DNA content of 5C above the endometrial cancer was 36.6%, proliferative endometrial, cystic endometrium Proliferation and endometrial hyperplasia were prolonged, followed by contents of 14.49%, 12.58% and 7.5% respectively; histological grade of endometrial carcinoma was grade Ⅲ only, grade Ⅳ did not appear, DNA content> 5C, grade Ⅰ Accounting for 27.66%, Ⅱ grade accounted for 29.34%, Ⅲ grade content increased dramatically up to 62.24%. It shows that the aneuploidy probability increases with the increase of disease grade, and it is considered that the determination of cell DNA in clinic can help to objectively judge the tumor biological characteristics.