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目的了解我院住院患者静脉用抗菌药物临床应用特点和存在问题,为进一步规范抗菌药物使用提供依据。方法对我院2010年11月～2011年11月静脉给药途径抗菌药物的使用情况作统计分析,并进行评估。结果共涉及13大类75个药品种类,其中以头孢菌素类占36.02%,青霉素类占21.57%,β-内酰胺酶抑制剂类占18.93%为主;数量最多的前6位为美洛西林钠12.99%,头孢噻肟钠9.49%,头孢他啶8.38%,头孢孟多酯钠6.08%,头孢哌酮钠/他唑巴坦钠5.53%,青霉素4.59%;使用抗菌药物最多的3个科室为骨外科30.15%,泌尿外科15.69%,心血管呼吸神经肾内科15.63%。其中用量前10位的抗菌药物中,一线用药两种,使用率为8.47%,二线用药三种,使用率为30.86%,三线用药两种,使用率为10.46%。结论我院住院患者静脉用抗菌药物选用上仍存在不合理性,应加强临床抗菌药物使用监控,提高临床合理用药水平。
Objective To understand the characteristics and existing problems of clinical application of intravenous antibiotics in hospitalized patients in our hospital and provide evidence for further standardizing the use of antibiotics. Methods The hospital from November 2010 to November 2011 intravenous route of use of antimicrobial agents for statistical analysis, and to assess. Results A total of 75 drug categories were involved in 13 major categories, of which 36.02% were cephalosporins, 21.57% were penicillins and 18.93% were β-lactamase inhibitors; the top 6 most frequent were Merlot Cefotaxime sodium was 12.99%, cefotaxime sodium was 9.49%, ceftazidime was 8.38%, cefadroxil sodium was 6.08%, cefoperazone sodium / tazobactam sodium was 4.53%, penicillin was 4.59%. The three departments with the most antibacterial drugs were bone surgery 30.15 %, Urology 15.69%, Cardiovascular Respiratory Nephrology 15.63%. Among the top 10 antibacterials, there are two kinds of first-line drugs, with the usage rate of 8.47% and the second-line drugs of three kinds, with the usage rate of 30.86% and the third-line drug usage rate of 10.46%. Conclusion In our hospital inpatient intravenous use of antimicrobial drugs there is still unreasonable, we should strengthen the monitoring of clinical use of antimicrobial agents, improve clinical rational use of medicine.