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小几特发性血小板减少性紫癜(ITP)和成人不同,以自限性的急性型为主,慢性型不过10~20%。本文对小儿期急性及慢性ITP的甲基强的松龙冲击疗法(m-PSL“Pu1se”疗法)和免疫球蛋白大量静注疗法(IVIg疗法)的效果进行比较。对象急性ITP17例,于发病后1周内未予治疗,初诊血小板低于2万/μl,伴有紫癜,粘膜出血等出血症状,其中用m-PSL“pulse”疗法7例,IVIg疗法12例。2例先用m-PSL“pu1se”,后用IVIg疗法。慢性ITP17例患病期间曾口服类固醇治疗,此次用m-PSL“pu1se”疗法5例,I VIg疗法14例。2例分别间隔2个月及3个月采用两种治疗。
A small number of idiopathic thrombocytopenic purpura (ITP) and adults different to self-limited acute type, chronic type, but 10 to 20%. This article compares the effects of methylprednisolone stroke therapy (m-PSL “Pu1se” therapy) and immunoglobulin massively intravenous therapy (IVIg therapy) on acute and chronic ITP in infancy. Subjects with acute ITP in 17 cases were treated with no treatment within 1 week after onset, and newly diagnosed platelets were less than 20,000 / μl with bleeding symptoms such as purpura and mucosal hemorrhage. Among them, 7 cases were treated with m-PSL “pulse” and 12 cases with IVIg . 2 cases first with m-PSL “pu1se”, followed by IVIg therapy. Chronic ITP17 cases during the period had oral steroid therapy, the use of m-PSL “pu1se” therapy in 5 cases, 14 cases of I VIg therapy. Two patients were treated with two treatments at intervals of 2 months and 3 months respectively.