目的 分析优质护理对消化性溃疡致上消化道出血患者心理状态、生活质量的影响。方法 选取2019年2月至2021年2月我院收治的消化性溃疡致上消化道出血患者104例，按入院先后顺序分为研究组（52例，行优质护理）与对照组（52例，行常规护理）。比较两组患者的心理状态、生活质量、并发症及护理满意度。结果 干预前，两组焦虑、抑郁发生率以及SF-36评分比较，差异无统计学意义（P＞0.05）；干预后，研究组焦虑、抑郁发生率低于干预前及对照组，SF-36评分明显高于干预前及对照组，差异有统计学意义（P＜0.05）。干“,”Objective To analyze the impact of high-quality nursing care on the psychological status and quality of life of patients with upper gastrointestinal bleeding caused by peptic ulcer. Methods A total of 104 patients with upper gastrointestinal hemorrhage caused by peptic ulcer admitted to our hospital from February 2019 to February 2021 were selected and divided into study group (52 cases， used high-quality nursing) and control group (52 cases， used routine nursing). The psychological state， quality of life， complications and nursing satisfaction of the two groups of patients were compared. Results Before the intervention， there was no significant difference in the incidence of anxiety and depression and the SF-36 score between the two groups (P＞0.05); after the intervention， the incidence of anxiety and depression in the study group was lower than that before the intervention and the control group， and the SF-36 score of the study was significantly higher than that before nursing and the control group， there were significant differences (P＜0.05). After the intervention，the total complication rate of the study group was significantly lower than that of the control group， and the nursing satisfaction was significantly higher than that of the control group (P＜0.05). Conclusion The application of high-quality nursing care to patients with upper gastrointestinal bleeding caused by peptic ulcer can reduce the incidence of anxiety and depression and the incidence of complications， and improve the quality of life and nursing satisfaction of patients.