近年来雷公藤广泛应用于临床,在治疗各种肾小球疾病方面也取得较好效果,但伴随出现的一些药物副反应,如肝脏毒副作用亦逐渐为人们所重视.我们自1992年5月至 1997年5月,对317例原发性肾病综合征(PNS)应用雷公藤治疗进行了临床观察,其中84例出现肝脏毒副作用.结果报告如下. In recent years, Tripterygium wilfordii has been widely used in clinic, and has achieved good results in the treatment of various glomerular diseases, but with the emergence of some side effects of drugs, such as the side effects of liver toxicity has gradually been valued by people .We since 1992 To May 1997, 317 patients with primary nephrotic syndrome (PNS) were treated with triptolide clinical observation, of which 84 cases of liver toxicity. The results are reported as follows.