In view of the fact that wet-cloth facial masks are complicated in components and low in utilization efficiency of active ingredients, an all-solid-state nanofiber facial mask was innovatively developed. In the paper, brief introductions were given to the formation mechanism, microstructure and structural features of the nanofiber facial mask. High-molecular polymer and active ingredients were directly turned into nano cellosilk and a piece of nanofiber membrane of micrometer thick was span onto the receiving base cloth. Compared with common wet-cloth facial mask, nanofiber facial mask has less additive ingredients but works more effectively. For example, it is easy to apply, good at water retention, excellent in loading capacity and biocompatibility. The paper ended with existing problems with materials of all-solid-state nanofiber facial mask, its development orientation and application prospect.