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用免疫酶组化法对１２１例各型临床肝炎患者和１０８名献血员进行了抗－ＣＶＢＩｇＭ和ＩｇＧ检测。两组的阳性率分别为９．９％、１９．８％和８．３％、３６．１％，总阳性率分别是２５．６％和４０．７％；非乙型肝炎患者抗－ＣＶＢＩｇＭ和ＩｇＧ及总阳性率为１３．８％、２４．１％和３１．０％，乙肝患者抗－ＣＶＢＩｇＭ、ＩｇＧ及总阳性率分别为６．３％、１５．９％和２０．６％。肝炎患者，尤其是乙肝患者抗－ＣＶＢＩｇＧ及总阳性率与对照组差异有显著性。结果提示：乙肝患者可能对ＣＶＢ感染的免疫应答较低，因此其抗－ＣＶＢ检出率低；也可能是因为ＨＢＶ感染后，对再感染ＣＶＢ有干扰作用之故。其详细机理有待进一步研究
121 cases of various clinical hepatitis and 108 blood donors were tested for anti-CVBIgM and IgG using immunoenzyme histochemistry. The positive rates of the two groups were 9.9%, 19.8% and 8.3%, 36.1%, respectively, and the positive rates were 25.6% and 40.7% respectively. Anti-CVBIgM IgG and total positive rate were 13.8%, 24.1% and 31.0%, anti-CVBIgM, IgG and total positive rate of hepatitis B were 6.3%, 15.9% and 20.6% respectively. The anti-CVBIgG and the total positive rate of hepatitis patients, especially hepatitis B patients, were significantly different from the control group. The results suggest that: hepatitis B patients may have lower immune response to CVB infection, so its anti-CVB detection rate is low; may also be due to HBV infection, re-infection of CVB interference. The detailed mechanism needs further study