论文部分内容阅读
目的探讨超声下未成熟卵泡抽吸术(immature follicle aspiration,IMFA)治疗多囊卵巢综合征(polycystic ovary syndrome,PCOS)不孕症患者的疗效及对患者内分泌功能的影响。方法选取2013年1月-2015年1月在湖南省妇幼保健院治疗的94例PCOS不孕症患者,采用随机数字表分为IMFA组(IMFA治疗)、对照组(采用达英-35治疗)各47例,对比两组的疗效及内分泌相关指标。结果治疗后,IMFA组患者的血清中睾酮(Testosterone,T)、黄体生成素(luteinizing hormone,LH)均低于对照组,卵泡刺激素(follicle stimulating hormone FSH)高于对照组,差异均具有统计学意义(P<0.05),两组患者的空腹胰岛素(fasting insulin,INS)水平差异无统计学意义(P>0.05),IMFA组患者的卵巢体积、阻力指数(resistance index,RI)均低于对照组,卵巢动脉最大血流速度(maximum blood flow velocity,Vmax)高于对照组,差异均具有统计学意义(P<0.05),IMFA组患者的月经恢复率63.83%、妊娠率44.68%均高于对照组的36.17%、23.40%(P<0.05)。结论超声下IMFA治疗PCOS不孕症患者能更显著的改善患者内分泌水平、促进卵巢形态及功能恢复、提高患者的月经恢复及妊娠率。
Objective To investigate the effect of immature follicle aspiration (IMFA) on infertility patients with polycystic ovary syndrome (PCOS) under ultrasound and its effect on the endocrine function of the patients. Methods From January 2013 to January 2015, 94 cases of PCOS infertility treated in Hunan MCH were randomly divided into three groups: IMFA group (IMFA group) and control group (up to Ying-35 group) 47 cases in each group. The curative effect and endocrine related index of two groups were compared. Results After treatment, the serum testosterone (T), luteinizing hormone (LH) in IMFA group were lower than those in control group, and follicle stimulating hormone FSH was higher than that in control group (P <0.05). There was no significant difference in the fasting insulin (INS) between the two groups (P> 0.05). The ovarian volume, resistance index (RI) In the control group, the maximum blood flow velocity (Vmax) of ovarian artery was higher than that of the control group (P <0.05). The IMFA group’s menstrual recovery rate was 63.83% and the pregnancy rate was 44.68% 36.17% of the control group, 23.40% (P <0.05). Conclusion Ultrasound treatment of PCOS infertility patients with PCOS can significantly improve the patient’s endocrine levels and promote ovarian morphological and functional recovery, improve patient’s menstrual recovery and pregnancy rate.