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目的 探讨壶腹周围癌区域性胰腺切除(regionalpancreatectomy ,RP)术后胃瘫(postopertivegastroparesissyndrome ,PGS)的病因、发生机制及治疗方法。方法 回顾性分析2 1例壶腹周围癌RP术后PGS的临床资料及诊疗过程。结果 PGS多发生于RP术后6～14d ;经分阶段营养支持、改善胃肠动力等保守治疗,PGS多在术后4周内消除。结论 RP术后PGS的病因复杂;采取保守支持治疗是治疗RP术后PGS的有效手段,分阶段营养支持是治疗的重要措施;不宜采用手术治疗。
Objective To investigate the etiology, pathogenesis and treatment of postoperational gastroparesyndrome (PGS) after regional pancreatectomy (RP). Methods The clinical data and diagnosis and treatment of PGS in 21 cases of periampullary carcinoma after RP were retrospectively analyzed. Results PGS mostly occurred in 6-14 days after operation of RP. After the staged nutritional support, gastrointestinal motility and other conservative treatment were improved. PGS was mostly eliminated within 4 weeks after operation. Conclusions The cause of PGS after RP is complex. Adopting conservative supportive therapy is an effective way to treat PGS after RP. Staged nutrition support is an important measure to treat PGS. Surgical treatment should not be used.