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目的:探讨控制性降压在减少鼻咽血管纤维瘤术中出血的应用价值。方法:将32例鼻咽血管纤维瘤患者随机分为控制性降压组和对照组,每组各16例。控制性降压组在全麻下用硝普钠(sodium nitropruddide,SNP)进行降压,并对血流动力学和血气分析变化进行观察。结果:控制性降压组出血量为(465．5±146．7)ml,对照组出血量为(1454．5±289．3)ml;降压组手术时间为(90．92±28．3)min,对照组为(160．5±97．8)min,两组术中出血量和手术时间比较均有显著差异(P＜0．01)。结论:控制性降压是减少鼻咽血管纤维瘤术中出血的一种有效方法。
Objective: To investigate the value of controlled hypotension in reducing intraoperative bleeding of nasopharyngeal angiofibroma. Methods: Thirty-two patients with nasopharyngeal angiofibroma were randomly divided into controlled hypotensive group and control group, with 16 cases in each group. The controlled hypotensive group was depressurized with sodium nitroprudide (SNP) under general anesthesia and the changes of hemodynamics and blood gas analysis were observed. Results: The amount of bleeding in controlled hypotension group was (465.5 ± 146.7) ml, while that in control group was (1454.5 ± 289.3) ml. The duration of operation in hypotensive group was (90.92 ± 28. 3) min in the control group and (160.5 ± 97.8) min in the control group, respectively. There was significant difference between the two groups in the amount of bleeding and the operation time (P <0.01). Conclusion: Controlled hypotension is an effective method to reduce intraoperative bleeding in nasopharyngeal angiofibroma.