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目的探索腰围身高比值是否能更好地反映肥胖对成人高血压的影响。方法以“腰围身高比值”或“腰围/身高比”或“腰围/身高”、“高血压”、“ROC”等为关键词或主题词,检索中外重要数据库,同时追溯相关参考文献。采用Meta分析方法,分性别以体质指数(BMI)、腰围(WC)、腰臀比(WHR)及腰围身高比值(WHTR)对高血压调查对象的工作曲线(ROC)下面积(AUC)作为评价指标,利用Stata9.2软件进行统计分析。结果共纳入8篇文献。全部人群男、女性WHTR的AUC(95%CI)分别为0.680(0.645～0.714)和0.718(0.676～0.761);对以中国人群为研究对象的3项研究进行亚组分析,男、女性WHTR的AUC(95%CI)分别为0.686(0.637～0.736)和0.795(0.770～0.819)。与BMI、WC及WHR相比,无论男女,均是WHTR对高血压的AUC合并值最大,但差别无统计学意义(P>0.05)。中国女性WHTR的合并值大于男性,差别有统计学意义(P<0.05)。结论WHTR可能比BMI、WHR、WC能更好地反映肥胖对成人尤其是对中国成年女性高血压的影响。
Objective To explore whether the waist-height ratio can better reflect the effect of obesity on adult hypertension. Methods The key words or keywords of “waist circumference height ratio” or “waist circumference / height ratio” or “waist circumference / height”, “high blood pressure”, “ROC” Database, while tracking related references. Meta-analysis was used to evaluate the area under the working curve (ROC) of hypertensive subjects based on body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR) and waist circumference ratio (WHTR) Indicators, the use of Stata 9.2 software for statistical analysis. Results A total of 8 articles were included. The AUC (95% CI) of WHTR for all men and women were 0.680 (0.645-0.714) and 0.718 (0.676-0.761), respectively. A subgroup analysis of 3 Chinese studies was performed on male and female WHTR AUC (95% CI) were 0.686 (0.637-0.736) and 0.795 (0.770-0.819), respectively. Compared with BMI, WC and WHR, no significant difference was found between ATR and WHTR (P> 0.05). The combined value of WHTR in Chinese women was greater than that in men, with a significant difference (P <0.05). Conclusions WHTR may better reflect the effects of obesity on adult and especially Chinese adult female hypertension than BMI, WHR and WC.