大量杀灭白血病细胞与诱导白血病细胞向正常成熟细胞分化,是目前治疗研究重点之一。本文2例,先用联合化疗,以求最大限度杀灭增殖期为主的白血病细胞,以减少白血病细胞产生的增殖因子(Prolif-eration factor),然后在维持缓解阶段,采用小剂量化疗药物等以巩固治疗,取得了一些效果,现已存活5年,报告如下: 病例1:高××,女,45岁,已婚,工人。因乏力、关节痛半年余,见皮下出血点而于1985年10月17日入院。查体轻度贫血貌,腘窝、腹股沟、腹部见散在出血点,胸骨有叩痛,心肺未发现异常,肝肋下1.5厘米、脾大1厘米,血红蛋白100克/L,白细胞 A large number of kill leukemia cells and induce leukemia cells to normal mature cells is one of the focus of treatment. This article 2 cases, first with the combination of chemotherapy, in order to maximize the killing of proliferative phase-based leukemia cells in order to reduce the leukemic cells produced by the proliferation factor (Prolif-eration factor), and then maintain the remission phase, the use of low-dose chemotherapy drugs To consolidate the treatment, and achieved some results, has now survived 5 years, the report is as follows: Case 1: high × ×, female, 45 years old, married, workers. Due to fatigue, joint pain more than six months, see the subcutaneous bleeding point and in October 17, 1985 admission. Examination of mild anemia appearance, popliteal fossa, groin, abdomen see the scattered bleeding point, sternal bone percussion, no abnormal heart and lung, hepatic ribs 1.5 cm, splenomegaly 1 cm, hemoglobin 100 g / L, white blood cells