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目的总结脑磁图(magnetoencephalography,MEG)描记与术中唤醒联合应用切除功能区胚胎发育不良性神经上皮瘤(dysembroplastic neuroepithelial tumor,DNT)的经验。方法根据MEG结果大体确定功能区范围,在唤醒麻醉下应用术中皮质电刺激刺激相应区域皮质,明确功能区和DNT边界。在显微镜下切除DNT 4例,观察治疗效果。结果 4例患者手术效果良好,无功能区损害。长期随访未出现癫发作及DNT复发。结论联合应用MEG与术中唤醒技术显微镜下切除肿瘤是治疗功能区DNT安全、有效的方法。
Objective To summarize the experience of excision of dysembroplastic neuroepithelial tumor (DNT) with magnetoencephalography (MEG) and intraoperative awakening. Methods According to the results of MEG, the range of functional area was generally determined. The intracortical electrical stimulation was used to stimulate the corresponding cortical area under awakening anesthesia. The functional area and the boundary of DNT were identified. Under the microscope, 4 cases were treated with DNT and the therapeutic effect was observed. Results 4 cases of patients with good results, no functional area damage. Long-term follow-up did not appear epileptic seizures and DNT recurrence. Conclusions Combined use of MEG and intraoperative arousal technique under microscope for tumor removal is a safe and effective method for the treatment of DNT in functional areas.