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目的 :研究肾病综合征患者在治疗前后抗凝血酶Ⅲ (AT -Ⅲ )的变化及临床价值。方法 :分正常对照组、肾病综合征治疗前及治疗后三组 ,应用全自动血凝仪测定AT -Ⅲ活性。结果 :肾病综合征治疗前比正常对照组明显降低 (P <0 0 1) ,肾病综合征治疗后AT -Ⅲ含量明显升高 ,与治疗前及正常对照组比较有显著性差异 (P <0 0 1)。结论 :对肾病综合征患者抗凝血酶Ⅲ含量的检测 ,有助于临床治疗及疗效观察 ,防止血栓形成
Objective: To study the changes and clinical value of antithrombin Ⅲ (AT-Ⅲ) in patients with nephrotic syndrome before and after treatment. Methods: The normal control group, nephrotic syndrome before and after treatment three groups, the application of automatic coagulation analyzer AT-Ⅲ activity. Results: The nephrotic syndrome was significantly lower than that of the normal control group before treatment (P <0.01). The content of AT-III in nephrotic syndrome group was significantly higher than that in the normal control group (P <0.01) 0 1). Conclusion: The detection of antithrombin Ⅲ in patients with nephrotic syndrome is helpful for the clinical treatment and observation of curative effect, preventing thrombosis