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[目的]评价动脉灌注化疗对ⅢB期宫颈癌的疗效。[方法]以动脉插管化疗及腔内镭疗各 1个疗程治 76例ⅢB期宫颈癌;对照组是同期标准放疗的ⅢB期患者; 1组用X线体外放疗54例,2组体外放疗用60Co有70例,全部患者随诊10年以上。[结果]三组患者的10年生存率分别是:研究组为61.9%,对照1组是37.0%(P=0.25),对照2组有44.3%(P=0.28)。研究组患者治疗后无放射性直肠炎等并发症。 1例经1个疗程化疗的ⅡB期宫颈癌,治后无癌生存18年。[结论]合理的化疗加腔内放疗可以治愈ⅢB期宫颈癌,并减少放疗并发症。
[Objective] To evaluate the curative effect of arterial infusion chemotherapy on stage Ⅲ B cervical cancer. [Method] With 76 cases of stage ⅢB cervical cancer treated by arterial intubation and intraluminal radiotherapy, the control group was stage ⅢB with standard radiotherapy in the same period. One group received radiotherapy with X-ray in 54 cases and the other two groups received radiotherapy in vitro With 60Co 70 cases, all patients followed up for more than 10 years. [Results] The 10-year survival rates were 61.9% in the study group, 37.0% in the control group 1 (P = 0.25) and 44.3% in the control group 2 (P = 0 .28). The study group had no complications such as radiological proctitis after treatment. One case of stage Ⅱ B cervical cancer after a course of chemotherapy, cancer-free survival after 18 years. [Conclusion] The reasonable chemotherapy plus intracavitary radiotherapy can cure stage Ⅲ B cervical cancer and reduce the complications of radiotherapy.