目的探讨女性各期梅毒感染情况和治疗结果。方法对415例女性梅毒患者通过临床症状和梅毒的抗体血清学检验进行诊断,通过问诊、回访、填写性病报告卡对感染、治疗情况进行分析。结果 415例女性梅毒患者,一期梅毒24例,占5.78%;二期梅毒9例,占2.16%;隐性梅毒382例,占92.05%。梅毒感染中,20岁以下22例,占5.30%;20~29岁159例,占38.31%;30~39岁144例,占34.69%。治愈387例,占93.25%;血清固定28例,占6.75%。无业人员134例,占32.29%;农民工153例,占36.86%;工人56例,占13.49%;干部42例,占10.12%;教师10例,占2.40%;其它行业19例,占4.57%。结论女性梅毒感染有年轻化趋势,应引起全社会的重视。加强女性农民工和无业人员梅毒筛查,做好血清固定患者的治疗和沟通解释,减轻患者压力。加强女性梅毒的预防宣传,提高女性自我防护意识,早发现、早诊断、早治疗,有效减少梅毒传播。 Objective To investigate the prevalence of syphilis in women and the treatment outcome. Methods A total of 415 female patients with syphilis were diagnosed by serological tests of clinical symptoms and syphilis. The infection and treatment were analyzed through interrogation, return visit and STD report card. Results 415 cases of female patients with syphilis, a syphilis in 24 cases, accounting for 5.78%; 9 cases of secondary syphilis, accounting for 2.16%; 382 cases of latent syphilis, accounting for 92.05%. Syphilis infection in 22 cases under the age of 20, accounting for 5.30%; 159 cases of 20 to 29 years old, accounting for 38.31%; 30 to 39-year-old 144 cases, accounting for 34.69%. 387 cases cured, accounting for 93.25%; 28 cases of serum fixation, accounting for 6.75%. 134 were unemployed people, accounting for 32.29%; 153 were migrant workers, accounting for 36.86%; 56 were workers, accounting for 13.49%; 42 were cadres, accounting for 10.12%; 10 were teachers, accounting for 2.40%; 19 were other industries, accounting for 4.57% . Conclusions There is a tendency of younger female syphilis infection, which should arouse the attention of the whole society. Strengthen female migrant workers and unemployed people syphilis screening, do a good job of treatment and communication of patients with fixed serum explain, reduce patient pressure. Strengthen prevention and publicity for female syphilis and raise awareness of female self-protection. Early detection, early diagnosis and early treatment effectively reduce the spread of syphilis.