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目的探讨沙盘游戏联合泰必利治疗儿童多发性抽动症的疗效研究。方法 30例多发性抽动症儿童被随机分配到治疗组和对照组。治疗组采用泰必利口服,疗程12周,剂量50～100mg/次,3次/d,同时接受8次沙盘游戏治疗,1次/周,50min/次;对照组口服单药泰必利,剂量同治疗组。治疗前和治疗后应用耶鲁抽动症严重程度评分量表(YGTSS)观察抽动总分的变化情况,对沙盘游戏联合泰必利治疗儿童多发性抽动症的疗效进行评价。结果经过12周治疗后,治疗组YGTSS总分从治疗前(24.13±4.19)分下降至治疗末的(9.07±4.32)分;对照组从治疗前(23.93±4.35)分下降至(12.27±3.71)分。两组相比在治疗第12周末YGTSS总分差异有统计学意义(P<0.01)。结论沙盘游戏联合泰必利能有效治疗儿童多发性抽动症。
Objective To investigate the therapeutic effect of sand table game combined with tiapride on children with multiple tic. Methods Thirty children with TS were randomly assigned to treatment group and control group. The treatment group was treated with tiapride orally, the course of treatment was 12 weeks, the dosage was 50 ~ 100mg / time, 3 times / d, while 8 times of sand table games were treated, once / week, 50min / times; Dose with the treatment group. Before treatment and after treatment, the Yale tic disorder severity scale (YGTSS) was used to observe the changes of tic scores, and evaluate the efficacy of sand table game combined with tiapride in the treatment of children with Tourette. Results After 12 weeks of treatment, the total score of YGTSS in the treatment group decreased from 24.13 ± 4.19 to 9.07 ± 4.32 and the control group decreased from 23.93 ± 4.35 to 12.27 ± 3.71 )Minute. The difference of YGTSS scores between the two groups at the end of the 12th week was statistically significant (P <0.01). Conclusion Sand table game combined with tiapride can effectively treat children with Tourette’s disease.