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目的探讨小儿结核性脑膜炎的影像学特点、治疗方法及转归。方法回顾性分析2010年8月至2012年8月我院收治的46例小儿结核性脑膜炎患者的临床资料。结果本组46例患者中40例(87.0%)临床症状、体征好转,脑脊液部分或全部指标恢复正常,出院后继续抗结核治疗;4例(8.7%)临床症状、体征、脑脊液指标均无明显好转;2例(4.3%)病情恶化自动出院;1例(2.2%)死亡,死于呼吸循环衰竭。结论小儿结核性脑膜炎的发病现象复杂、发病原因多样,尽早诊断、尽早治疗是改善本病预后的关键。
Objective To investigate the imaging features, treatment and prognosis of children with tuberculous meningitis. Methods The clinical data of 46 cases of children with tuberculous meningitis admitted from August 2010 to August 2012 in our hospital were retrospectively analyzed. Results All the 46 patients (87.0%) had clinical symptoms and signs improved and some or all indicators of cerebrospinal fluid returned to normal. After discharge, they continued anti-TB treatment. No symptoms, signs and cerebrospinal fluid indexes were found in 4 cases (8.7%) 2 cases (4.3%) were discharged automatically; 1 case (2.2%) died of respiratory failure. Conclusions The incidence of tuberculous meningitis in children is complex and the causes are diverse. Early diagnosis and early treatment are the keys to improve the prognosis of this disease.