本试验结果表明钙拮抗剂尼莫地平、尼群地平及硝苯啶均显著降低轻、中度原发性高血压患者(n=199)的血压,降压效力尼群地平>硝苯啶>尼莫地平,副作用均较轻。尼群地平似有一定降血胆固醇作用。根据此结果与以往资料,我们初步认为,尼莫地平对轻、中度高血压尤其是伴有脑血管疾患患者的防治应是有益的;尼群地平对高血压或伴有高胆固醇血症患者的治疗可能是较好的;硝苯啶对高血压或伴有冠心病患者的治疗是合适的。 The results showed that nimodipine, nitrendipine and nifedipine were significantly reduced the blood pressure and antihypertensive effect of nifedipine> nifedipine in patients with mild to moderate essential hypertension (n = 199) Nimodipine, side effects are lighter. Nitrendipine seems to have a hypocholesterolemic effect. Based on this result and previous data, we initially believe that nimodipine should be beneficial to the prevention and treatment of patients with mild to moderate hypertension, especially with cerebrovascular disease; nitrendipine should be beneficial to patients with hypertension or hypercholesterolemia Of the treatment may be better; nifedipine for the treatment of hypertension or patients with coronary heart disease is appropriate.