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目的探究铝碳酸镁与奥美拉唑联合治疗十二指肠球部溃疡的临床疗效。方法 68例十二指肠球部溃疡患者,随机分为对照组和观察组,各34例,对照组单纯采用奥美拉唑治疗,观察组采用铝碳酸镁与奥美拉唑联合治疗,治疗后观察比较两组患者临床疗效和不良反应情况。结果观察组患者治疗总有效率为97.1%,对照组患者治疗总有效率为85.3%,观察组患者治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗后两组患者均未发生任何严重不良反应,不影响总体治疗效果。结论采用铝碳酸镁与奥美拉唑联合治疗十二指肠球部溃疡,能够有效缓解患者临床症状,缩小溃疡面积,患者未发生任何严重不良反应,临床疗效显著。
Objective To investigate the clinical efficacy of combination of magnesium aluminum carbonate and omeprazole in the treatment of duodenal ulcer. Methods 68 cases of duodenal ulcer patients were randomly divided into control group and observation group, 34 cases in each group. The control group was treated with omeprazole alone. The observation group was treated with combination of aluminum magnesium carbonate and omeprazole. After the observation and comparison of clinical efficacy and adverse reactions in both groups. Results The total effective rate was 97.1% in observation group and 85.3% in control group, and the total effective rate in observation group was higher than that in control group (P <0.05). After treatment, the two groups None of the patients had any serious adverse reactions and did not affect the overall therapeutic effect. Conclusion The combination of aluminum magnesium carbonate and omeprazole in the treatment of duodenal ulcer can effectively alleviate the clinical symptoms and reduce the ulcer area in patients without any serious adverse reactions, and the clinical effect is significant.