论文部分内容阅读
目的:探讨心肌肌钙蛋白I(cTnI)在新生儿高胆红素血症中的变化及意义。方法:对67例新生儿高胆红素血症患儿及50例生理性黄疸健康儿,在黄疸极期(黄疸最明显时)、黄疸减退期(黄疸减退一半时)和黄疸消退后验cTnI、间接胆红素(IBIL)。结果:(1)生理性黄疸组各期cTnI值基本一致,相互比较差异不明显(P>0.1)。(2)在黄疸极期高胆红素血症组cTnI明显增高,与生理性黄疸组比较差异显著(P<0.01)。(3)经治疗后随IBIL的降低cTnI也随之下降,3个时期相互比较差异均有显著性(P<0.01)。(4)cTnI值与IBIL值呈高度正相关(r=0.874,P<0.01)。结论:新生儿高胆红素血症可引起心肌损害,IBIL越高损害越明显。检测cTnI对高胆红素血症的治疗有指导意义。
Objective: To investigate the changes of cardiac troponin I (cTnI) in neonatal hyperbilirubinemia and its significance. Methods: 67 cases of neonatal hyperbilirubinemia and 50 cases of physiological jaundice healthy children, jaundice in the extreme (jaundice most obvious), jaundice in jaundice (jaundice halfway) and jaundice after cTnI , Indirect bilirubin (IBIL). Results: (1) The cTnI values of physiological jaundice group were basically the same, but the difference was not significant (P> 0.1). (2) The cTnI of hyperbilirubinemia group was significantly higher than that of physiological jaundice group (P <0.01). (3) After treatment, the cTnI decreased with the decrease of IBIL. The differences between the three periods were significant (P <0.01). (4) There was a positive correlation between cTnI and IBIL (r = 0.874, P <0.01). Conclusion: Neonatal hyperbilirubinemia can cause myocardial damage, the more damage the more obvious IBIL. Detection of cTnI for the treatment of hyperbilirubinemia has guiding significance.