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目的观察氨茶碱联合环磷腺苷葡胺(心先安)治疗病态窦房结综合征的疗效。方法59例病态窦房结综合征患者,停用一切影响心率、心律的药物3d。口服氨茶碱0.1g,3次/d,同时静脉给予心先安120～180mg/d,14d为1个疗程,观察治疗前后临床症状、心电图及24h动态心电图。结果显效37例(62.7%),有效6例(27.1%),无效16例(10.2%),总有效率为89.8%。结论氨茶碱联合心先安治疗病态窦房结综合征疗效确切,部分病例可替代起搏器治疗。
Objective To observe the efficacy of aminophylline combined with cyclic adenosine monophosphate (AMI) in the treatment of sick sinus syndrome. Methods 59 patients with sick sinus syndrome, disable all affect heart rate, heart rate drugs 3d. Oral aminophylline 0.1g, 3 times / d, while intravenous heart Xianan 120 ~ 180mg / d, 14d for a course of treatment before and after treatment to observe the clinical symptoms, ECG and 24h dynamic electrocardiogram. The results were effective in 37 cases (62.7%), effective in 6 cases (27.1%), ineffective in 16 cases (10.2%), the total effective rate was 89.8%. Conclusion The combination of aminophylline and Xin Xiangan is effective in treating patients with sick sinus syndrome. In some cases, it can replace the pacemaker.