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目的:观察盐酸戊乙奎醚对异丙酚伍用氯胺酮麻醉用于无痛人工流产术的影响。方法:实施无痛人工流产术的患者204例,随机分为A、B两组,A组静脉缓慢注入异丙酚2 mg/kg+氯胺酮0.2~0.3 mg/kg混合液;B组静脉注射盐酸戊乙奎醚0.01 mg/kg,15 min后静脉缓慢注入异丙酚与氯胺酮混合液。观察并记录患者术中口腔分泌物分泌情况及术后恶心呕吐等不良反应的发生率、了解宫颈松弛程度。结果:宫颈松弛程度B组明显优于A组(P<0.05),B组术中口腔分泌物增多的发生率和术后恶心呕吐、下腹坠痛的发生率明显低于A组(P<0.01)。结论:盐酸戊乙奎醚可改善异丙酚伍用氯胺酮用于无痛人工流产术的麻醉效果。
Objective: To observe the effect of penehyclidine hydrochloride on anesthesia with propofol and ketamine in painless artificial abortion. Methods: A total of 204 patients with painless induced abortion were randomly divided into two groups: group A and group B, propofol 2 mg / kg and ketamine 0.2 ~ 0.3 mg / kg were slowly injected into group A. Group B received intravenous injection of Acetochlor 0.01 mg / kg, 15 min after the slow intravenous infusion of propofol and ketamine mixture. Observation and record of patients with intraoperative oral secretions and postoperative nausea and vomiting secretion of adverse reactions, to understand the degree of cervical relaxation. Results: The degree of cervical relaxation was significantly better in group B than in group A (P <0.05). The incidence of oral secretions and postoperative nausea and vomiting in group B were significantly lower than those in group A (P <0.01) ). CONCLUSION: Penehyclidine hydrochloride improves the anesthetic effect of propofol with ketamine on painless artificial abortion.