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目的探讨剖宫产术后产妇硬膜外连续注射罗哌卡因与吗啡对泌乳素的影响。方法选取68例足月初产妇作为研究对象,按照数字抽签法将其随机分为两组,试验组产妇行硬膜外连续麻醉镇痛,对照组产妇术后即拔出硬膜外麻醉导管,对两组产妇行血浆泌乳素指标检测,评价术后持续麻醉对泌乳素的影响。结果试验组产妇术后24h与48h疼痛评分均低于对照组产妇(P<0.05);术后试验组产妇泌乳素指标明显高于对照组(P<0.05);试验组产妇初乳分泌时间与肛门排气时间明显短于对照组(P<0.05)。结论剖宫产术后行硬膜外罗哌卡因与吗啡注射持续麻醉能促进初乳分泌,镇痛有效性与安全性均十分显著,可在临床推广应用。
Objective To investigate the effect of epidural continuous ropivacaine and morphine on prolactin after cesarean section. Methods A total of 68 full-term primiparae were selected as the study subjects. They were randomly divided into two groups according to the digital lottery method. The epidural anesthesia analgesia was performed in the experimental group and the epidural catheter was withdrawn in the control group Two groups of maternal serum prolactin index test to assess the impact of continuous postoperative anesthesia on prolactin. Results The pain scores of the experimental group at 24h and 48h postoperatively were all lower than that of the control group (P <0.05). The index of prolactin in the experimental group was significantly higher than that of the control group (P <0.05) Anal exhaust time was significantly shorter than the control group (P <0.05). Conclusion Continuous anesthesia with epidural ropivacaine and morphine injection after cesarean delivery can promote the secretion of colostrum. The analgesic efficacy and safety are both very significant and can be popularized and applied clinically.