黄连始载于《神农本草经》,《中国药典》(2015版)收载黄连为毛茛科植物黄连Coptis chinensisF ranch.、三角叶黄莲Coptis deltoidea C.Y.Cheng et Hsiao或云连Coptis teeta Wall.的干燥根茎。具有清热燥湿、泻火解毒的功效。主含原小檗碱型生物碱,含有小檗碱、巴马汀、黄连碱、药根碱、甲基黄连碱、木蓝碱等[1]。不同的黄连的有效成分也不同,迄今己得数十种生物碱类成 Coptis chinensisF ranch., Coptis deltoidea C.Y.Cheng et Hsiao or Coptis teeta Wall., Contained in the Chinese Pharmacopoeia (2015 edition), are the original rhizomes of Coptis. With heat dampness, purging fire detoxification effect. The main containing berberine alkaloids, containing berberine, palmatine, berberine, jatrorrhizine, methyl berberine, such as blue alkali [1]. The different active ingredients of Coptis are also different, so far have dozens of alkaloids into