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硝普钠(Nitroprusside)是一种血管扩张剂。1929年 Johnson 首先用于临床,认为有快速降血压作用。但直到1955年,Page 等提出硝普钠静脉滴注是安全有效的用药方法以后,才被一些医院用作治疗高血压急症的首选药物。1972年 Franciosa 用于改善急性心肌梗塞左室功能取得良好效果。此后用硝普钠治疗各种心脏病所致急慢性心力衰竭的人日益增多,而且都取得了较好的疗效。 国内亦有个别研究报导。然而对近年在克山病新发病例中占大多数的、治疗效果不够理想的亚急型克山病(亚急克)和慢型
Nitroprusside is a vasodilator. Johnson first used in clinical in 1929, that there is a rapid hypotensive effect. However, until 1955, Page et al proposed sodium nitroprusside intravenous infusion is a safe and effective drug treatment method, only by some hospitals for the treatment of hypertensive emergency drug of choice. Franciosa in 1972 to improve acute myocardial infarction with good left ventricular function. Since then, the use of sodium nitroprusside to treat various heart diseases caused by an increasing number of people with acute and chronic heart failure, and have achieved good results. There are also some domestic research reports. However, in recent years, Keshan disease cases accounted for the majority of new cases, the treatment effect is not ideal subacute Keshan disease (subacute grams) and slow