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EB病毒属疱疹病毒科γ亚科中唯一能引起人类感染的淋巴滤泡病毒。近40年来的研究证明,EBV与多种人类血液系统疾病密切相关(如传染性单核细胞增多症、EBV相关的噬血细胞增多综合征、伯基特淋巴瘤等),由于EBV对人类的普遍易感性,因而,近年有关EBV的免疫学特性、EBV逃避机体免疫应答的机制、EBV感染相关疾病的致病机制等研究有了很大进展,就相关问题进行综述。
The Epstein-Barr virus is the only lymphoblastoid virus in the subfamily of Herpesviridae that causes human infection. Nearly 40 years of research have shown that EBV is closely related to various human diseases of the blood system (such as infectious mononucleosis syndrome, EBV-associated hemophagocytic syndrome, Burkitt’s lymphoma, etc.). Because EBV is common to humans Therefore, in recent years, great progress has been made on the immunological characteristics of EBV, the mechanism of EBV evading the body’s immune response and the pathogenesis of EBV-related diseases, and the related issues are reviewed.