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目的对2011年唐山市路南区117例手足口病患儿进行病原学调查,为手足口病的防治提供科学依据。方法采集手足口病患儿的疱疹液、粪便、咽拭子进行提取肠道病毒RNA;进一步经RT-PCR检测。结果从117例患儿共采集153份标本,68例为CA16(58.1%),22例为EV71(18.8%),其他27例(23.1%);年龄别发病,6岁以下发病(112例)较多,4～9月发病率最高。结论手足口病患儿检测到的主要病原是CA16和EV71,发病与气候条件有关。
Objective To investigate the etiological investigation of 117 cases of hand-foot-mouth disease in Lunan District of Tangshan City in 2011, providing a scientific basis for the prevention and treatment of hand-foot-mouth disease. Methods Herpes simplex, herpes and throat swabs were collected for the extraction of enterovirus RNA from the children with HFMD and further detected by RT-PCR. Results A total of 153 specimens were collected from 117 children, including 68 cases with CA16 (58.1%), 22 cases with EV71 (18.8%) and 27 cases (23.1%) with age-related onset and 112 cases with age below 6 years More, 4 to 9 months the highest incidence. Conclusion The main pathogens detected in children with hand-foot-mouth disease are CA16 and EV71, and the incidence is related to the climatic conditions.