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咽喉反流(laryngopharygeal reflux,LPR)是指胃内容物向上反流至上呼吸消化道,从而导致一系列的食管外症状,如慢性咳嗽、声音嘶哑、消化不良、吞咽困难、咽喉部异物感、哮喘。研究显示,有10%的耳鼻咽喉科就诊患者患有LPR。其可导致慢性喉炎、接触性肉芽肿、声门下狭窄等疾病,乃至喉癌。该疾病的症状、体征缺乏特异性,导致其诊断和治疗标准不明确。因此,临床中对此病的认识有待深化,仍然呈现出诊断过度、治疗不规范。本文对LPR诊断方法的研究进展进行综述。
Laryngopharygeal reflux (LPR) refers to the reflux of gastric contents up the upper respiratory tract, resulting in a series of extra-esophageal symptoms such as chronic cough, hoarseness, indigestion, dysphagia, foreign body sensation in the throat, asthma . Studies show that 10% of patients treated for otolaryngology have LPR. It can cause chronic laryngitis, contact granuloma, subglottic stenosis and other diseases, and even laryngeal cancer. The disease symptoms, signs of lack of specificity, resulting in its diagnosis and treatment of the standard is not clear. Therefore, the clinical understanding of the disease need to be deepened, still showing a diagnosis of over-treatment is not standardized. This article reviews the progress of LPR diagnostic methods.